Hydroxychloroquine EP impurity D-d<sub>5</sub>

Pathways Recommended:	Vitamin D Related/Nuclear Receptor

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By Research Areas:	Cancer (728) Cardiovascular Disease (209) Endocrinology (197) Infection (382) Inflammation/Immunology (341) Metabolic Disease (338) Neurological Disease (365)
Click Chemistry:	Azide (2) Alkynes (13)

Targets Recommended: P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-143941S

Hydroxychloroquine EP impurity D-d5 dihydrochloride	Drug Metabolite Isotope-Labeled Compounds	Others
Hydroxychloroquine EP impurity D-d₅ (dihydrochloride) is the deuterium labeled Hydroxychloroquine EP impurity D dihydrochloride[1].

HY-142592S

Clozapine EP impurity D-d8

Drug Metabolite Isotope-Labeled Compounds Others

Clozapine EP impurity D-d₈ is the deuterium labeled Clozapine EP impurity D[1].
HY-144242S

Voriconazole EP impurity D-d3

Drug Metabolite Isotope-Labeled Compounds Others

Voriconazole EP impurity D-d₃ is the deuterium labeled Voriconazole EP impurity D[1].

*Clozapine EP impurity* D-d8**	Drug Metabolite Isotope-Labeled Compounds	Others
Clozapine EP impurity D-d₈ is the deuterium labeled Clozapine EP impurity D[1].

*Voriconazole EP impurity* D-d3**	Drug Metabolite Isotope-Labeled Compounds	Others
Voriconazole EP impurity D-d₃ is the deuterium labeled Voriconazole EP impurity D[1].

HY-131263

Hydroxychloroquine Impurity F	Drug Metabolite	Others
Hydroxychloroquine Impurity F is the impurity of Hydroxychloroquine. Hydroxychloroquine is a synthetic antimalarial agent which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Hydroxychloroquine is efficiently inhibits SARS-CoV-2 infection in vitro .

HY-131262

Hydroxychloroquine Impurity E 4-[(7-Chloro-4-quinolinyl)amino]-1-pentanol	SARS-CoV Toll-like Receptor (TLR)	Others
Hydroxychloroquine Impurity E is the impurity of Hydroxychloroquine. Hydroxychloroquine is a synthetic antimalarial agent which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Hydroxychloroquine is efficiently inhibits SARS-CoV-2 infection in vitro .

HY-121899

1-Oxo Ibuprofen Ibuprofen EP impurity J	Drug Metabolite	Others
1-Oxo Ibuprofen (Ibuprofen EP impurity J) is a degradation product and a potential impurity in preparations of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC₅₀s of 13 μM and 370 μM, respectively .

HY-107495

*Betahistine EP Impurity* C** NSC19005	Histamine Receptor	Inflammation/Immunology
Betahistine EP Impurity C (NSC19005) is an impurity of Betahistine . Betahistine is a potent, orally active and well-tolerated histamine H1 receptor agonist and H3 receptor antagonist used for the study of rheumatoid arthritis (RA) .

HY-Z1430S

(3R,4S)-Paroxetine-d4 hydrochloride (3R,4S)-BRL29060-d<sub>4sub> hydrochloride; (3R,4S)-BRL29060A-d<sub>4sub>	Drug Metabolite Isotope-Labeled Compounds	Others
Paroxetine EP impurity D-d₄ (hydrochloride) is deuterium labeled (3R,4S)-3-((benzo[d][1,3]dioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine (Paroxetine Impurity）.

HY-143907S

Atorvastatin EP impurity H-d5

Drug Metabolite Isotope-Labeled Compounds Others

Atorvastatin EP impurity H-d₅ is the deuterium labeled Atorvastatin EP impurity H[1].
HY-143990S

Modafinil EP impurity B-d5

Drug Metabolite Isotope-Labeled Compounds Others

Modafinil EP impurity B-d₅ is the deuterium labeled Modafinil EP impurity B[1].

*Atorvastatin EP impurity* H-d5**	Drug Metabolite Isotope-Labeled Compounds	Others
Atorvastatin EP impurity H-d₅ is the deuterium labeled Atorvastatin EP impurity H[1].

*Modafinil EP impurity* B-d5**	Drug Metabolite Isotope-Labeled Compounds	Others
Modafinil EP impurity B-d₅ is the deuterium labeled Modafinil EP impurity B[1].

HY-143982S

*Mianserin EP impurity* E-d4 hydrochloride**	Drug Metabolite Isotope-Labeled Compounds	Others
Mianserin EP impurity E-d₄ (hydrochloride) is the deuterium labeled Mianserin EP impurity E hydrochloride[1].

HY-144203S

Trospium EP impurity C-d8 chloride

Drug Metabolite Isotope-Labeled Compounds Others

Trospium EP impurity C-d₈ (chloride) is the deuterium labeled Trospium EP impurity C chloride[1].

*Trospium EP impurity* C-d8 chloride**	Drug Metabolite Isotope-Labeled Compounds	Others
Trospium EP impurity C-d₈ (chloride) is the deuterium labeled Trospium EP impurity C chloride[1].

HY-W069504S2

Propan-1-amine-d5 hydrochloride Propylammonium-dd<sub>5sub> Chloride	Isotope-Labeled Compounds	Others
Propan-1-amine-dd₅ hydrochloride is the deuterium labeled Propan-1-amine hydrochloride[1].

HY-143997S

*(Rac)-Nicotine EP impurity* A-d4 hydrochloride**	Drug Metabolite Isotope-Labeled Compounds	Others
(Rac)-Nicotine EP impurity A-d₄ (hydrochloride) is the deuterium labeled (Rac)-Nicotine EP impurity A hydrochloride[1].

HY-144221S

*Tiotropium bromide EP impurity* A-d6**	Drug Metabolite Isotope-Labeled Compounds	Others
Tiotropium bromide EP impurity A-d₆ is the deuterium labeled Tiotropium bromide EP impurity A[1].

HY-137768

*Captopril EP Impurity* B**	Drug Metabolite	Others
Captopril EP Impurity B is an impurity of Captopril. Captopril (SQ-14534), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC₅₀=0.025 μM) .

HY-137772

*Captopril EP Impurity* E**	Drug Metabolite	Others
Captopril EP Impurity E is an impurity of Captopril. Captopril (SQ-14534), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC₅₀=0.025 μM) .

HY-13204S2

rel-Biperiden EP impurity A-d5

Isotope-Labeled Compounds mAChR Neurological Disease

rel-Biperiden EP impurity A-d₅ is deuterium labeled Biperiden (hydrochloride).
HY-13204S3

rel-Biperiden EP impurity B-d5

Isotope-Labeled Compounds mAChR Neurological Disease

rel-Biperiden EP impurity B-d₅ is deuterium labeled Biperiden (hydrochloride).

*rel-Biperiden EP impurity* A-d5**	Isotope-Labeled Compounds mAChR	Neurological Disease
rel-Biperiden EP impurity A-d₅ is deuterium labeled Biperiden (hydrochloride).

*rel-Biperiden EP impurity* B-d5**	Isotope-Labeled Compounds mAChR	Neurological Disease
rel-Biperiden EP impurity B-d₅ is deuterium labeled Biperiden (hydrochloride).

HY-137769

*Captopril EP Impurity* C** 3-Mercaptoisobutyric acid	Drug Metabolite	Others
Captopril EP Impurity C is an impurity of Captopril. Captopril (SQ-14534), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC₅₀=0.025 μM) .

HY-W015332

*Captopril EP Impurity* D** 3-Bromoisobutyric acid	Drug Metabolite	Others
Captopril EP Impurity D is an impurity of Captopril. Captopril (SQ-14534), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC₅₀=0.025 μM) .

HY-W013886

*Captopril EP Impurity* J** S-Acetylcaptopril	Drug Metabolite	Others
Captopril EP Impurity J is an impurity of Captopril. Captopril (SQ-14534), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC₅₀=0.025 μM) .

HY-RS13999

SUB1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SUB1 Human Pre-designed siRNA Set A SUB1 Human Pre-designed siRNA Set A

HY-146227

DNA topoisomerase II inhibitor 1	Topoisomerase Apoptosis	Cancer
DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase .

HY-W336012S

*Metoprolol EP impurity* O-d7 hydrochloride**	Drug Metabolite Isotope-Labeled Compounds	Others
Metoprolol EP impurity O-d₇ (hydrochloride) is the deuterium labeled 3,3'-(Isopropylazanediyl)bis(1-(4-(2-methoxyethyl)phenoxy)propan-2-ol)[1].

HY-119359

5,6-Epoxy-13-cis retinoic acid

Isotretinoin EP impurity G
Others Others

5,6-Epoxy-13-cis retinoic acid (Isotretinoin EP impurity G) is a metabolite of 13-cis retinoic acid .

5,6-Epoxy-13-cis retinoic acid Isotretinoin EP impurity G	Others	Others
5,6-Epoxy-13-cis retinoic acid (Isotretinoin EP impurity G) is a metabolite of 13-cis retinoic acid .

HY-136589

*Verapamil EP Impurity* C hydrochloride** NSC-609249 hydrochloride	Calcium Channel P-glycoprotein Cytochrome P450	Metabolic Disease
NSC-609249 hydrochloride is an *impurity* of Verapamil (HY-14275). Verapamil is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor .

HY-131251

Cetirizine 3-chloro impurity

Drug Metabolite Others

Cetirizine 3-chloro impurity is an impurity of Cetirizine 3-chloro .
HY-131269

Febuxostat impurity 7

Drug Metabolite Others

Febuxostat impurity 7 is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K_i of 0.6 nM .
HY-131270

Febuxostat impurity 8

Drug Metabolite Others

Febuxostat impurity 8 is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K_i of 0.6 nM .
HY-131271

Febuxostat impurity 6

Drug Metabolite Others

Febuxostat impurity 6 is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K_i of 0.6 nM .

Cetirizine 3-chloro impurity	Drug Metabolite	Others
Cetirizine 3-chloro impurity is an impurity of Cetirizine 3-chloro .

*Febuxostat impurity* 7**	Drug Metabolite	Others
Febuxostat impurity 7 is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K_i of 0.6 nM .

*Febuxostat impurity* 8**	Drug Metabolite	Others
Febuxostat impurity 8 is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K_i of 0.6 nM .

*Febuxostat impurity* 6**	Drug Metabolite	Others
Febuxostat impurity 6 is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K_i of 0.6 nM .

HY-W031727S1

Hydroxychloroquine-d5	Autophagy SARS-CoV Toll-like Receptor (TLR) Parasite
Hydroxychloroquine-d₅ is the deuterium labeled Hydroxychloroquine[1]. Hydroxychloroquine is a synthetic antimalarial agent which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Hydroxychloroquine is efficiently inhibits SARS-CoV-2 infection in vitro[2][3][4].

HY-W099680S1

Hexyltriphenylphosphonium-d5 bromide hexyl(triphenyl)phosphonium-d<sub>5sub>	Isotope-Labeled Compounds	Others
Hexyltriphenylphosphonium-dd₅ bromide is the deuterium labeled Hexyltriphenylphosphonium bromide[1].

HY-131272

Febuxostat dicarboxylic acid impurity	Drug Metabolite	Others
Febuxostat dicarboxylic acid impurity is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K_i of 0.6 nM .

HY-131273

Febuxostat amide impurity

Drug Metabolite Others

Febuxostat amide impurity is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K_i of 0.6 nM

Febuxostat amide impurity	Drug Metabolite	Others
Febuxostat amide impurity is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K_i of 0.6 nM

HY-133777

*Ciprofibrate impurity* A**	PPAR	Cancer
Ciprofibrate impurity A is an impurity of Ciprofibrate. Ciprofibrate (Win35833) is a potent peroxisome proliferator, increases the phosphorylation level of the PPARalpha .

HY-B1370B

(R)-Hydroxychloroquine (R)-HCQ	Parasite Toll-like Receptor (TLR) SARS-CoV Autophagy	Infection
(R)-Hydroxychloroquine is the enantiomer of Hydroxychloroquine . Hydroxychloroquine is a synthetic antimalarial agent which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Hydroxychloroquine is efficiently inhibits SARS-CoV-2 infection in vitro .

HY-100663

*Gefitinib impurity* 2**	EGFR	Others
Gefitinib impurity 2 is the impurity of Gefitinib. Gefitinib (ZD1839; HY-50895) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC₅₀ of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC₅₀ of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy. Gefitinib has antitumour activity .

HY-134686

*Edoxaban impurity* 4**	Factor Xa Thrombin	Cardiovascular Disease
Edoxaban impurity 4 is an impurity of Edoxaban. Edoxaban (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor with K_is of 0.561 nM and 2.98 nM for free FXa and prothrombinase, respectively. Edoxaban is an anticoagulant agent and can be used for stroke prevention .

HY-133774

*Trityl olmesartan medoxomil impurity* III**	Drug Metabolite	Others
Trityl olmesartan medoxomil impurity III is an impurity of Trityl olmesartan medoxomil. Trityl olmesartan medoxomil is an intermediate of Olmesartan medoxomil .

HY-W031727S

Hydroxychloroquine-d4-1 sulfate	Isotope-Labeled Compounds Parasite Toll-like Receptor (TLR) SARS-CoV Autophagy	Infection Cancer
Hydroxychloroquine-d₄-1 (sulfate) is the deuterium labeled Hydroxychloroquine. Hydroxychloroquine is a synthetic antimalarial agent which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Hydroxychloroquine is efficiently inhibits SARS-CoV-2 infection in vitro[1][2][3].

HY-141410

Fluticasone dimer impurity	Drug Metabolite	Others
Fluticasone dimer impurity is a dimeric impurity of Fluticasone Propionate . Fluticasone propionate is a corticosteroid with comparatively high receptor affinity and topical activity .

HY-131255

Ziprasidone amino acid Ziprasidone impurity C; Ziprasidone open ring impurity	5-HT Receptor Dopamine Receptor	Neurological Disease
Ziprasidone amino acid (Ziprasidone Impurity C) is an impurity of Ziprasidone. Ziprasidone is a combined 5-HT (serotonin) and dopamine receptor antagonist. Ziprasidone exhibits potent effects of antipsychotic activity .

HY-131265

*Mesalamine impurity* P**	PPAR PAK NF-κB	Inflammation/Immunology Cancer
Mesalamine impurity P is an impurity of Mesalamine (HY-15027). 5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB .

HY-B1370A

(S)-Hydroxychloroquine (S)-HCQ	Parasite Toll-like Receptor (TLR) SARS-CoV Autophagy	Infection
(S)-Hydroxychloroquine ((S)-HCQ) is the enantiomer of Hydroxychloroquine . Hydroxychloroquine, a synthetic antimalarial agent, inhibits Toll-like receptor 7/9 (TLR7/9) signaling, and shows efficiently inhibits SARS-CoV-2 infection in vitro .

HY-122830

DD-03-171

Btk Cancer

DD-03-171 is a BTK, IKFZ1 and IKFZ3 degrader, the BTK IC₅₀ a value of 5.1 nM. DD-03-171 has an antiproliferative effect on mantle cell lymphoma (MCL) cells .

DD-03-171	Btk	Cancer
DD-03-171 is a BTK, IKFZ1 and IKFZ3 degrader, the BTK IC₅₀ a value of 5.1 nM. DD-03-171 has an antiproliferative effect on mantle cell lymphoma (MCL) cells .

HY-131276

Olmesartan lactone impurity	Angiotensin Receptor	Cardiovascular Disease
Olmesartan lactone impurity is a cyclic ester impurity of Olmesartan. Olmesartan is an angiotensin II receptor (AT1R) antagonist and has the potential for high blood pressure study .

HY-400785

*Dapagliflozin impurity* A**	Others	Cancer
Dapagliflozin impurity A (Compound A) is a dapagliflozin peroxide, a genotoxic impurity, can cause damage to human genetic material at very low concentrations, leading to genetic mutations and possibly tumorigenesis .

HY-W031727

*Hydroxychloroquine* Maximum Cited Publications 49 Publications Verification	Parasite Toll-like Receptor (TLR) SARS-CoV Autophagy	Infection Cancer
Hydroxychloroquine (HCQ) is a synthetic oral antimalarial drug that can be used in the study of malaria and autoimmune diseases such as systemic lupus erythematosus and rheumatoid arthritis. Hydroxychloroquine is a potent autophagic flux inhibitor with antiviral activity (such as SARS-CoV-2 virus) that inhibits Toll-like receptor 7/9 (TLR7/9) signaling ^[5] .

HY-B1370R

Hydroxychloroquine sulfate (Standard) HCQ sulfate (Standard)	Parasite Toll-like Receptor (TLR) SARS-CoV Autophagy	Infection Cancer
Hydroxychloroquine (sulfate) (Standard) is the analytical standard of Hydroxychloroquine (sulfate). This product is intended for research and analytical applications. Hydroxychloroquine sulfate (HCQ sulfate) is a synthetic antimalarial agent which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Hydroxychloroquine sulfate is efficiently inhibits SARS-CoV-2 infection in vitro .

Cat. No.	Product Name

HY-L066

FDA Approved & Pharmacopeial Drug Library

3450 compounds

New drug development is a time-consuming and high-cost process. Drug repurposing (also called drug repositioning, reprofiling or retasking) offers various advantages over developing an entirely new drug for a given indication. First, the risk of failure is lower. Second, the time frame for drug development can be reduced. Third, less investment is needed. Approved drugs and pharmacopoeia collected compounds have identified bioactivities, good pharmacokinetic characteristics and safety which are suitable for drug repurposing.

MCE owns a unique collection of 3450 compounds from approved institutions such as FDA, EMA, NMPA, PMDA, etc. or pharmacopoeia such as USP, BP, JP, etc. These compounds have well-characterized bioactivities, safety and bioavailability properties. MCE FDA Approved & Pharmacopeial Drug Library is a good tool for drug repurposing which could dramatically accelerate drug development.

Cat. No.	Product Name	Type

HY-D1752

JC-9

D-22421
Fluorescent Dyes/Probes

JC-9 (D-22421) is a green-fluorescent probe used for ratiometric calculation of mitochondrial membrane potential.

Cat. No.	Product Name	Type

HY-145794

ZA3-Ep10

Drug Delivery

ZA3-Ep10 is a zwitterionic lipid used in lipid nanoparticles formulation for in vivo RNA delivery and non-viral CRISPR/Cas gene editing.

HY-I0959

5-Chlorouracil Fluorouracil impurity	Biochemical Assay Reagents
5-Chlorouracil (Fluorouracil Impurity) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W127572

Glycerol-d8

1,2,3-Propanetriol-d<sub>8sub>; Glycerin-d<sub>8sub>
Biochemical Assay Reagents

Glycerol-d₈ is the deuterium labeled Glycerol[1].

HY-109541S

1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d58 DMPC-d<sub>58sub>	Drug Delivery
1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d₅₈ is deuterium labeled 1,2-Dimyristoyl-sn-glycero-3-phosphocholine. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid used in liposomes. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine

HY-109541S1

1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d4 DMPC-d<sub>4sub>	Drug Delivery
1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d₄ is deuterium labeled 1,2-Dimyristoyl-sn-glycero-3-phosphocholine. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid used in liposomes. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine

HY-109541S2

1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d9 DMPC-d<sub>9sub>	Drug Delivery
1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d₉ is deuterium labeled 1,2-Dimyristoyl-sn-glycero-3-phosphocholine. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid used in liposomes. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine

HY-109541S3

1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d13 DMPC-d<sub>13sub>	Drug Delivery
1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d₁₃ is deuterium labeled 1,2-Dimyristoyl-sn-glycero-3-phosphocholine. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid used in liposomes. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine

HY-109541S4

1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d63 DMPC-d<sub>63sub>	Drug Delivery
1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d₆₃ is deuterium labeled 1,2-Dimyristoyl-sn-glycero-3-phosphocholine. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid used in liposomes. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine

HY-109541S5

1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d67 DMPC-d<sub>67sub>	Drug Delivery
1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d₆₇ is deuterium labeled 1,2-Dimyristoyl-sn-glycero-3-phosphocholine. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid used in liposomes. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine

HY-109541S6

(Rac)-1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d72 (Rac)-DMPC-d<sub>72sub>	Drug Delivery
(Rac)-1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d₇₂ is deuterium labeled (Rac)-1,2-Dimyristoyl-sn-glycero-3-phosphocholine. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid used in liposomes. 1,2-Dimyristoyl-sn-glycero-3-ph

HY-W127840

Ethylene-d4-diamine

1,1,2,2-tetradeuterioethane-1,2-diamine-d<sub>4sub>
Biochemical Assay Reagents

Ethylene-d₄-diamine is the deuterium labeled Ethylene-diamine[1].

HY-154831

C22-Ceramide N-Behenoyl-D-erythro-sphingosine; Cer d18:1/22:0	Drug Delivery
C22-Ceramide (Cer d18:1/22:0) is an endogenous bioactive sphingolipid. C22-Ceramide reduces the propensity of C16-ceramide channel formation in isolated rat liver mitochondria and in liposomes .

HY-120973

Butaprost free acid

Biochemical Assay Reagents

(R)-Butaprost (free acid). Butaprost is a structural analog of prostaglandin E2 (PGE2) with good selectivity for the EP2 receptor subtype. Butaprost is frequently used pharmacologically to define the expression profile of EP receptors in various human and animal tissues and cells. Gardiner caused serious confusion about the structure of butaprost in 1986 when he reported that the epimer of butaprost showing this selective activity was the C-16 (R)-epimer ( See reference 2 and notes). To increase the binding affinity of (R)-butaprost to prostaglandin receptors, we removed the methyl ester of (R)-butaprost and recreated the native C-1 carboxylic acid. Prostaglandin free acids typically bind their cognate receptors with 10 to 100-fold higher affinity than the corresponding ester derivatives. The pharmacology of (R)-butaprost has not been carefully studied, but it is generally considered to be the less active C-16 epimer. (Note: In the 1986 Gardiner paper in the British Journal of Pharmacology, butaprost appears on page 46 under the designation TR 4979. The structure drawn is incorrect because the authors use and refer to the more active C - The 16 epimer, which is actually 16(S). The structure on page 46 shows the structure as 16(R). It was not until the late 1990s that careful studies in the United States and Japan correctly determined the actual structure of C-16 The type is 16(S) in a compound called butaprost.)

Cat. No.	Product Name	Target	Research Area

HY-P4457

Leuprolide Acetate EP Impurity D

Peptides Cancer

Leuprolide Acetate EP Impurity D is the impurity of Leuprolide (Leuprorelin) .
HY-P4454

Goserelin EP Impurity E

Peptides Cancer

Goserelin EP Impurity E is the impurity of Goserelin (HY-13673) .

HY-P10215

Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2	Peptides	Infection
Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2 (compound 40) is a potent **Plasmodium subtilisin-like protease 1 (SUB1)** inhibitor. SUB1-IN-1 shows IC₅₀ values of 12 nM and 10 nM against P. vivax and P. falciparum SUB1 (Pv- and PfSUB1), respectively .

HY-P5703

EP5-1	Bacterial Apoptosis Fungal	Infection
EP5-1 is an antimicrobial peptide. EP5-1 has antibacterial and antifungal activities. EP5-1 also shows antitumor activity against cancer cells, and induces cell apoptosis. EP5-1 has antiviral activity against pseudorabies virus (PRV) .

HY-P5702

EP3	Bacterial Apoptosis Fungal	Infection
EP3 is an antimicrobial peptide. EP3 has antibacterial and antifungal activities. EP3 inhibits E. gallinarum, P. pyocyanea, A. baumanii, K. terrigena with a MIC value of 12.85 μg/mL. EP3 also shows antitumor activity against cancer cells, and induces cell apoptosis .

HY-P5701

EP2	Bacterial Fungal	Infection
EP2 is an antimicrobial peptide. EP2 has antibacterial and antifungal activities. EP2 inhibits E. gallinarum, P. pyocyanea, A. baumanii, K. terrigena with a MIC value of 11.4 μg/mL .

HY-P3417

Amp1EP9	Bacterial	Infection
Amp1EP9 is an antimicrobial peptide. Amp1EP9 is a powerful tool for developing potent and nontoxic antimicrobial agents. Amp1EP9 has the potential for the research of multidrug-resistant bacterial infections .

HY-128696

Amlodipine aspartic acid impurity Amlodipine aspartate	Drug Metabolite	Cardiovascular Disease
Amlodipine aspartic acid impurity is the impurity of Amlodipine aspartic acid. Amlodipine aspartic acid is a calcium channel blocker with antihypertensive and antianginal properties.

HY-105173

Teverelix EP 24332	GnRH Receptor Histamine Receptor	Endocrinology Cancer
Teverelix (EP 24332) is a GnRH antagonist. Teverelix binds competitively and reversibly to GnRH receptors, thereby suppressing the release of LH and FSH. Teverelix can be used in the research of prostatic hyperplasia, endometriosis, and prostate cancer .

HY-P3426

BACE1-IN-10

Beta-secretase Cancer

BACE1-IN-10 is a potent BACE1 Inhibitor. BACE1-IN-10 shows sub-micromolar activity against recombinant BACE1 (rBACE1) .

HY-P5856

αA-Conotoxin PIVA	nAChR	Neurological Disease
αA-Conotoxin PIVA is a selective mouse musclenAChR inhibitor with IC₅₀ for adult and fetal mouse musclenAChR sub> values are 2.3 nM and 22 nM respectively. αA-Conotoxin PIVA can be used in the study of neurological diseases.

HY-P2274

Argifin	Parasite	Infection
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC₅₀s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively .

HY-N2466

Melanotan I 1 Publications Verification MT-I; [Nle4,D-Phe7]-α-MSH	Melanocortin Receptor	Neurological Disease Cancer
Melanotan I is a potent non-selective melanocortin receptor (MCR) agonist. Melanotan I is a synthetic analogue of α-melanocyte stimulating hormone (α-MSH) that stimulates melanogenesis. Melanotan I can induce skin tanning by mimicking the actions of a-MSH on the melanocortin type 1 receptors (MC1R) of melanocytes. Melanotan I can be used for the research of sun-induced skin cancer, melanoma, inflammation and male erectile dysfunction .

HY-P5499

CMV pp65(13-27)	Peptides	Others
CMV pp65(13-27) is a biological active peptide. (This peptide is derived from amino acid residues 13 to 27 of the 65k lower matrix phosphoprotein of the human cytomegalovirus. It contains a nine-amino-acid sequence (LGPISGHVL) that matches the consensus binding motif for a major histocompatibility complex H2-Dd T-cell epitope.)

HY-P4519

Ac-Lys(Ac)-D-Ala-D-Lactic acid

Peptides Others

Ac-Lys(Ac)-D-Ala-D-Lactic acid is a depsipeptide substrate for penicillin-sensitive D-alanine carboxypeptidases (DD-carboxypeptidases) .

HY-W010452S1

3-Hydroxybutyric acid-13C4 sodium β-Hydroxybutyric acid-¹³C<sub>4sub> sodium	Endogenous Metabolite	Metabolic Disease
3-Hydroxybutyric acid- ¹³C₄ (sodium) is the ¹³C labeled 3-Hydroxybutyric acid sodium (HY-W010452). 3-Hydroxybutyric acid sodium is a metabolite that is elevated in type I diabetes, and can modulate the properties of membrane lipids[1].

HY-P4503

(D-His1)-Exenatide

Peptides Others

(D-His1)-Exenatide is one od impurities of Exenatide.
HY-P4459

(Des-Gly2)-Exenatide

Peptides Metabolic Disease

(Des-Gly2)-Exenatide is a potential impurity of Exenatide (HY-13443).

HY-P4755

*N-((RS)-2-Hydroxy-propyl)-Val-Leu-anilide*	Peptides	Others
N-((RS)-2-Hydroxy-propyl)-Val-Leu-anilide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-158104

LPPM-8	Peptides	Others
LPPM-8 is a ligand of Med25 and an inhibitor of Med25 protein-protein interactions (PPIs). LPPM-8 engages Med25 through interaction with the H2 face of its Activator Interaction Domain and stabilizes full-length protein in the cellular proteome. LPPM-8 is an orthosteric inhibitor of H2-binding transcriptional activators (such as ATF6a). LPPM-8 can be used for studying Med25 and Mediator complex biology .

HY-P1182

C21

Histone Methyltransferase Cancer

C21 is a potent, irreversible, and selective PRMT1 inhibitor with an IC₅₀ of 1.8 μM. C21 inhibits PRMT6 with an IC₅₀ of 8.8 μM .

HY-59121A

Isopropyl ((R)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate	Peptides	Infection
Isopropyl ((R)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate can be used to synthesis Sofosbuvir (HY-15005) to avoid the production of sofibuvir degradation impurities .

HY-P4407

(D-Asn28)-Exenatide

Peptides Metabolic Disease

(D-Asn28)-Exenatide is an Exenatide (HY-13443) impurity. Exenatide is a long-acting glucagon-like peptide-1 receptor agonist .
HY-P4410

(D-Asp28)-Exenatide

Peptides Metabolic Disease

(D-Asp28)-Exenatide is an Exenatide (HY-13443) impurity. Exenatide is a long-acting glucagon-like peptide-1 receptor agonist .

HY-P3517

β-Endorphin (6-31), human β-EP (6-31), human	Opioid Receptor	Neurological Disease Endocrinology
β-Endorphin, an endogenous opioid neuropeptide, is an opioid receptor agonist. β-Endorphin binds preferentially to μ-opioid receptors and is produced in certain neurons of the central and peripheral nervous system and is one of three endorphins produced in humans. β-Endorphin can be used to reduce stress and maintain homeostasis in the body and is involved in neurological pain perception regulation .

HY-P2286

D-3

Phosphatase Cancer

D-3, a phosphorpeptide, is an efficient, simple, and specific iPSC-eliminating agent .
HY-P0013

Antide

D-21074; ORF 23541
GnRH Receptor Cancer

Antide (D-21074) is a potent LHRH antagonist. Antide also can be used for the research of prostatic cancer.
HY-P4480

H-Phe-Phe-Phe-Phe-OH

Peptides Others

H-Phe-Phe-Phe-Phe-OH is a tetrapeptide that can generate vertically aligned, highly ordered 3-D bionanostructures .

HY-16375

Ozarelix D-63153	GnRH Receptor Apoptosis	Cancer
Ozarelix (D-63153) is a GnRH antagonist. Ozarelix induces cell apoptosis and arrests cell in G2/M phase. Ozarelix can be used in the research of prostate cancer .

HY-125357

Ternatin	Peptides	Metabolic Disease
Ternatin (compound 2) is a cyclic heptapeptides that can be isolated from mushroom Coliorus versicolor. Ternatin inhibits fat-accumulation with an IC₅₀ of 0.027 μM in 3T3-L1 adipocytes .

Cat. No.	Product Name

HY-K1041

Seamless DNA Assembly Plus Kit
MCE Seamless DNA Assembly Plus Kit contains an optimized mix of recombinase, reaction buffer, and additional cofactors that significantly improve the cloning efficiency and tolerance to impurities. This product can complete multiple DNA fragments recombination and takes only 5 minutes for single fragment, and the positive rate is more than 95%.

Cat. No.	Product Name	Target	Research Area

HY-P99294

Ganitumab AMG 479; Human Anti-IGF1R Recombinant Antibody	IGF-1R	Cancer
Ganitumab (AMG 479) is a recombinant human monoclonal antibody to the human type 1 insulin-like growth factor receptor (IGF1R). Ganitumab recognizes murine IGF1R with sub-nanomolar affinity (K_D=0.22 nM) and inhibits the interaction of murine IGF1R with IGF1 and IGF2. Ganitumab can be used in research of cancer .

HY-P990193

Anti-Mouse MHC Class I (H-2Kd, H-2Dd) Antibody (34-1-2S)	Inhibitory Antibodies	Others
Anti-Mouse MHC Class I (H-2Kd, H-2Dd) Antibody (34-1-2S) is a mouse-derived IgG2a, κ type antibody inhibitor, targeting to mouse MHC Class I.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-125833

Alpha-Naphthoflavone 5 Publications Verification	Flavonoids Flavones Source classification Indigofera heterantha Wall. ex Brand. Plants Compositae Disease Research Fields Cancer	Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis
Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis .

HY-P5703

EP5-1	Structural Classification Animals Ketones, Aldehydes, Acids Source classification	Bacterial Apoptosis Fungal
EP5-1 is an antimicrobial peptide. EP5-1 has antibacterial and antifungal activities. EP5-1 also shows antitumor activity against cancer cells, and induces cell apoptosis. EP5-1 has antiviral activity against pseudorabies virus (PRV) .

HY-P5702

EP3	Structural Classification Animals Ketones, Aldehydes, Acids Source classification	Bacterial Apoptosis Fungal
EP3 is an antimicrobial peptide. EP3 has antibacterial and antifungal activities. EP3 inhibits E. gallinarum, P. pyocyanea, A. baumanii, K. terrigena with a MIC value of 12.85 μg/mL. EP3 also shows antitumor activity against cancer cells, and induces cell apoptosis .

HY-P5701

EP2	Structural Classification Animals Ketones, Aldehydes, Acids Source classification	Bacterial Fungal
EP2 is an antimicrobial peptide. EP2 has antibacterial and antifungal activities. EP2 inhibits E. gallinarum, P. pyocyanea, A. baumanii, K. terrigena with a MIC value of 11.4 μg/mL .

HY-N11799

Neochilenin 3-O-Methylquercetin 4′-O-glucoside	Structural Classification Flavonoids Source classification Plants Compositae Other Flavonoids	Others
Neochilenin (3-O-Methylquercetin 4 '-O-glucoside) is a glycoside of 3-O-methylquercetin, which can be isolated from the sub-family Cereoideae (Cactaceae). .

HY-W011474

Geranylgeraniol	Natural Products Microorganisms	NF-κB
Geranylgeraniol is an orally acitve vitamin K₂ sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model .

HY-W778546

7-epi-10-Deacetyl baccatin III	Structural Classification Terpenoids Source classification Taxaceae Diterpenoids Plants Taxus baccata L.	Others
7-epi-10-Deacetyl baccatin III can be isolated from the degradation impurities in Docetaxel (HY-B0011) .

HY-P2274

Argifin	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Parasite
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC₅₀s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively .

HY-N10192

Aculene D	Infection Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Source classification Disease Research Fields	Endogenous Metabolite Bacterial
Aculene D, a fungal metabolite, shows quorum sensing (QS) inhibitory activity against Chromobacterium violaceum CV026, and could significantly reduce violacein production in N-hexanoyl-l-homoserine lactone (C6-HSL) induced C. violaceum CV026 cultures at sub-inhibitory concentrations .

HY-N0662

Amentoflavone 5+ Cited Publications Didemethyl-ginkgetin	Structural Classification Flavonoids Classification of Application Fields Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Disease Research Fields Selaginella tamariscina (P. Beauv.) Spring Cancer	Reactive Oxygen Species Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase .

HY-W778547

7-epi-10-Oxo-10-deacetyl baccatin III 10-Dehydrobaccatin V	Structural Classification Terpenoids Source classification Taxaceae Diterpenoids Plants Taxus baccata L.	Others
7-epi-10-Oxo-10-deacetyl baccatin III (10-Dehydrobaccatin V) can be isolated from the degradation impurities in Docetaxel (HY-B0011) .

HY-B0504S

Creatinine-d3 NSC13123-d<sub>3sub>	Classification of Application Fields Metabolic Disease Disease Research Fields	Endogenous Metabolite
Creatinine-d₃ is a deuterium labeled Creatinine. Creatinine is a break-down product of creatine phosphate in muscle[1].

HY-112023

Lumisterol 3 (>90%) 9β,10α-Cholesta-5,7-dien-3β-ol; Cholecalciferol EP impurity C	Structural Classification Human Gut Microbiota Metabolites Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
Lumisterol 3 (>90%) (9β,10α-Cholesta-5,7-dien-3β-ol) is a normal human secosterooid metabolite from the class of vitamin D3 photoisomer derivatives. Lumisterol 3 (>90%) is used in the preparation of vitamin D .

HY-B0131

Prostaglandin E1 Maximum Cited Publications 9 Publications Verification Alprostadil; PGE1	Cardiovascular Disease Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields	Prostaglandin Receptor Endogenous Metabolite
Prostaglandin E1 (Alprostadil) is a prostanoid receptor ligand, with K_is of 1.1 nM, 2.1 nM, 10 nM, 33 nM and 36 nM for mouse EP3, *EP4, EP2, IP and EP1*, respectively. Prostaglandin E1 induces vasodilation and inhibits platelet aggregation. Prostaglandin E1 can be used as a vasodilator for the research of peripheral vascular diseases .

HY-B0131R

Prostaglandin E1 (Standard) Alprostadil(Standard); PGE1 (Standard)	Cardiovascular Disease Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields	Prostaglandin Receptor Endogenous Metabolite
Prostaglandin E1 (Standard) is the analytical standard of Prostaglandin E1. This product is intended for research and analytical applications. Prostaglandin E1 (Alprostadil) is a prostanoid receptor ligand, with K_is of 1.1 nM, 2.1 nM, 10 nM, 33 nM and 36 nM for mouse EP3, *EP4, EP2, IP and EP1*, respectively. Prostaglandin E1 induces vasodilation and inhibits platelet aggregation. Prostaglandin E1 can be used as a vasodilator for the research of peripheral vascular diseases .

HY-N10069

Bonducellin	Structural Classification Flavonoids Leguminosae Caesalpinia sappan L. Source classification Plants Other Flavonoids	Others
Bonducellin is a a homoisoflavonoid, which can be isolated from Caesalpinia digyna roots. Bonducellin is a potent inhibitor of efflux pump (EP), while EP induces resistance in mycobacteria and serves as a target of anti-TB (tuberculosis) agents. Bonducellin reduces MIC of EtBr by 8-fold against M. smegmatis (MIC=62.5 mg/L) .

HY-113205

15-keto-Prostaglandin E2 15-keto-PGE2	Structural Classification Ketones, Aldehydes, Acids Marine algae Marine natural products Source classification	Endogenous Metabolite Prostaglandin Receptor STAT PPAR
15-keto-Prostaglandin E2 is an endogenous metabolite. 15-keto-Prostaglandin E2 inhibits STAT3 activation by binding to its Cys259 residue. 15-keto-Prostaglandin E2 can bind and stabilize *EP2* and *EP4* receptor. 15-keto-Prostaglandin E2 inhibits breast cancer cell growth and progression. 15-keto-Prostaglandin E2 activates PPAR-γ and promotes fungal growth .

HY-N7748A

Epi-cryptoacetalide	Terpenoids Labiatae Samanea saman (Jacq.) Merr. Diterpenoids Plants	Estrogen Receptor/ERR Prostaglandin Receptor
Epi-cryptoacetalide is a natural diterpenoid. Epi-cryptoacetalide reveals high affinity to ER-α and PGE2 receptor (EP2 subtype) with K_i values of 0.3 μM and 1.92 μM, respectively. Epi-cryptoacetalide has anti-endometriosis activities .

HY-118442

Sphingosine (d14:1) Tetradecasphing-4-enine	Natural Products Classification of Application Fields Animals Source classification Disease Research Fields Cancer	PKC
Sphingosine (d14:1) (Tetradecasphing-4-enine), a sphingolipid, is a potent Protein kinase C (PKC) inhibitor. Sphingosine (d14:1) prevents its interaction with sn-1,2-diacylglycerol (DAG)/Phorbol esters .

HY-117081

*C30(ω-hydroxy) Ceramide (d18:1/30:0)*	Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Others
C30(ω-hydroxy) Ceramide (d18:1/30:0), a sphingolipid, is an epidermis-specifically vital component of the water barrier in mammalian skin. C30(ω-hydroxy) Ceramide (d18:1/30:0) is expressed in epidermal keratinocytes and male germ cells during their differentiation and maturation. C30(ω-hydroxy) Ceramide (d18:1/30:0) deficiency in the epiderm of Elovl4 deletion or mutation mice .

HY-141579

Sphingosine (d17:1)	Animals Source classification	Others
Sphingosine (d17:1) is a 17-carbon sphingosine found in human skin. Sphingosine (d17:1) can be phosphorylated by sphingosine kinases to produce C-17 sphingosine-1-phosphate. Sphingosine C-17 was used as an internal standard for spectral analysis of sphingoid compounds .

HY-145520

*(±)-2'-hydroxy* Ceramide (d18:0/18:0)** (±)-2'-hydroxy Cer(d18:0/18:0)	Structural Classification Natural Products Neurological Disease Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
(±)-2'-hydroxy Ceramide (d18:0/18:0) is a sphingomyelin that can be isolated from mammalian platelets stimulation by ADP .

HY-135176

13-Dihydrocarminomycin	Quinones Structural Classification Anthraquinones Source classification Endogenous metabolite	Endogenous Metabolite
13-Dihydrocarminomycin (compound D788-12) is the major metabolite of the antitumor antibiotic Carminomycin (HY-B2171). 13-Dihydrocarminomycin has weak antitumor activity .

HY-N8425

Octacosanoic acid Montanic acid	Classification of Application Fields Croton caudatus Geisel. Croton. Ketones, Aldehydes, Acids Source classification Metabolic Disease Euphorbiaceae Plants Disease Research Fields	Endogenous Metabolite
Octacosanoic acid is a very long-chain saturated fatty acid. It is the major component of D-003, a mixture of very long-chain aliphatic acids purified from sugar cane wax that has antiplatelet and cholesterol-lowering activities in animal models .

HY-133537

Hygrolidin	Infection Structural Classification Microorganisms Antifungal Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Disease Research Anticancer Disease Research Fields	Antibiotic Fungal ADC Cytotoxin
Hygrolidin is a 16-membered macrolide antibiotic produced by Streptomyces hygroscopicus D-1166. Hygrolidin has anti-fungus activity against Valsa ceratosperma. Hygrolidin induces p21 expression and abrogates cell cycle progression at G1 and S phases. Hygrolidin has antitumor activity .

Species:	Human (22) Rhesus Macaque (2) Mouse (8) Rat (4) Cynomolgus (2)
Tag:	GFP (3) SUMO (5) His (29) Tag Free (4) Strep (3) Myc (1) Trx (1) Fc (6)
Source:	HEK293 (18) E. coli Cell-free (4) CHO (1) Sf9 insect cells (1) P. pastoris (1) E. coli (15)

Cat. No.	Compare	Product Name	Species	Source

HY-P7280

	PDGF-DD Protein, Human (CHO) 1 Publications Verification rHuPDGF-DD; Platelet-derived growth factor D; SCDGFB	Human	CHO
	PDGF-DD Protein, Human (CHO) is a member of the PDGF family, specifically binds to and activates its cognate receptor PDGFR-β, and participates in regulating cancer proliferation, transformation, and invasion through activating multiple downstream oncogenic pathways, resulting in tumor development and progression.

HY-P74650

	*PC4/SUB1 Protein, Human (His)* Activated RNA polymerase II transcriptional coactivator p15; PC4; p14; sub1; RPO2TC1	Human	E. coli
	The PC4/SUB1 protein acts as a multifunctional coactivator that cooperates with TAF to promote functional interactions between upstream activators and the general transcription machinery. Its role extends to the potential stability of multiprotein transcription complexes. PC4/SUB1 Protein, Human (His) is the recombinant human-derived PC4/SUB1 protein, expressed by E. coli , with N-His labeled tag. The total length of PC4/SUB1 Protein, Human (His) is 127 a.a., with molecular weight of ~19 kDa.

HY-P71518

	H2-D1 Protein, Mouse (His-SUMO) H2-D1; H-2 class I histocompatibility antigen; D-D alpha chain; H-2D(D)	Mouse	E. coli
	The H2-D1 protein is a key element of the immune system and is actively involved in the presentation of foreign antigens. As a major histocompatibility complex class I (MHC-I) component, H2-D1 forms a heterodimer with α and β chains and is essential for recognizing and presenting antigen to cytotoxic T cells. H2-D1 Protein, Mouse (His-SUMO) is the recombinant mouse-derived H2-D1 protein, expressed by E. coli , with N-His, N-SUMO labeled tag. The total length of H2-D1 Protein, Mouse (His-SUMO) is 287 a.a., with molecular weight of ~49.2 kDa.

HY-P701031

	PDGF-DD Protein, Cynomolgus (HEK293, His) PDGF-D; SCDGF-B; IEGF; SCDGFB	Cynomolgus	HEK293
	The PDGF-DD protein is a key growth factor with critical regulatory effects on embryonic development, cell proliferation, migration, survival, and chemotaxis. It is a potent mitogen for mesenchymal cells and plays a crucial role in wound healing. PDGF-DD Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived PDGF-DD protein, expressed by HEK293 , with N-His labeled tag. The total length of PDGF-DD Protein, Cynomolgus (HEK293, His) is 352 a.a., with molecular weight of 50-65 kDa.

HY-P72430

	VEGF-DD Protein, Mouse (HEK293, His) Vascular endothelial growth factor D; VEGF-D; FIGF	Mouse	HEK293
	VEGF-DD Protein, a versatile growth factor, orchestrates angiogenesis, lymphangiogenesis, and endothelial cell growth. It stimulates proliferation, migration, and influences vessel permeability. VEGF-DD binds VEGFR-3, triggering crucial signaling for vascular development. Structurally, VEGF-DD is a non-covalent homodimer, emphasizing its intricate role in vascular processes. VEGF-DD Protein, Mouse (HEK293, His) is the recombinant mouse-derived VEGF-DD protein, expressed by HEK293 , with C-6*His labeled tag. The total length of VEGF-DD Protein, Mouse (HEK293, His) is 109 a.a., with molecular weight of 17-20 kDa.

HY-P73474

	VEGF-DD Protein, Mouse (HEK293, Fc) Vascular endothelial growth factor D; VEGF-D; FIGF	Mouse	HEK293
	VEGF-DD Protein, a versatile growth factor, orchestrates angiogenesis, lymphangiogenesis, and endothelial cell growth. It stimulates proliferation, migration, and influences vessel permeability. VEGF-DD binds VEGFR-3, triggering crucial signaling for vascular development. Structurally, VEGF-DD is a non-covalent homodimer, emphasizing its intricate role in vascular processes. VEGF-DD Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived VEGF-DD protein, expressed by HEK293 , with N-hFc labeled tag. The total length of VEGF-DD Protein, Mouse (HEK293, Fc) is 109 a.a., with molecular weight of ~45 & 36 kDa, respectively.

HY-P73475

	VEGF-DD Protein, Rat (HEK293, Fc) Vascular endothelial growth factor D; VEGF-D; FIGF	Rat	HEK293
	VEGF-DD, a growth factor, stimulates proliferation, migration, and vessel permeability. It is crucial for vascular development and maintenance of lymphatic endothelium. VEGF-DD binds and activates VEGFR-3, initiating essential signaling pathways. Structurally, it forms a non-covalent homodimer, playing an intricate role in vascular processes. VEGF-DD Protein, Rat (HEK293, Fc) is the recombinant rat-derived VEGF-DD protein, expressed by HEK293 , with N-hFc labeled tag. The total length of VEGF-DD Protein, Rat (HEK293, Fc) is 117 a.a., with molecular weight of ~50 kDa.

HY-P73040

	Erythropoietin Protein, Rat (sf9, His) ECYT5; EP; EPO; EPoetin; Erythropoietin; MVCD2	Rat	Sf9 insect cells
	Epo protein is a hormone that plays a vital role in regulating red blood cell production in the body. It stimulates the differentiation and maturation of red blood cells in the bone marrow. Erythropoietin Protein, Rat (sf9, His) is the recombinant rat-derived Erythropoietin protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of Erythropoietin Protein, Rat (sf9, His) is 166 a.a., with molecular weight of ~27 kDa.

HY-P75222

	Erythropoietin Protein, Cynomolgus (HEK293, His) ECYT5; EP; EPO; EPoetin; Erythropoietin; MVCD2	Cynomolgus	HEK293
	Erythropoietin Protein is a glycoprotein cytokine secreted mainly by the kidneys in response to cellular hypoxia. It regulates erythrocyte growth and balance. EPO binding to its receptor (EPOR) triggers EPOR dimerization, activating JAK2. This initiates downstream events involving effectors like STAT1 and STAT3, crucial for erythrocyte proliferation, differentiation, and maintaining optimal blood cell levels. Erythropoietin Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Erythropoietin protein, expressed by HEK293 , with C-His, C-10*His labeled tag. The total length of Erythropoietin Protein, Cynomolgus (HEK293, His) is 165 a.a., with molecular weight of ~19.7 kDa.

HY-P73038

	Erythropoietin/EPO Protein, Mouse (HEK293, solution) ECYT5; EP; EPO; EPoetin; Erythropoietin; MVCD2	Mouse	HEK293
	This gene encodes the erythropoietin (EPO) protein that is critical for regulating erythropoiesis. It is mainly expressed in the liver during fetal development and is transferred to the kidneys in adults. Erythropoietin/EPO Protein, Mouse (HEK293, solution) is the recombinant mouse-derived Erythropoietin/EPO protein, expressed by HEK293 , with tag free. The total length of Erythropoietin/EPO Protein, Mouse (HEK293, solution) is 166 a.a., with molecular weight of ~18.6 kDa.

HY-P70495

	VEGF-DD Protein, Human (HEK293, His) Vascular Endothelial Growth Factor D; VEGF-D; c-Fos-Induced Growth Factor; FIGF; VEGFD	Human	HEK293
	VEGF-DD protein is a potent growth factor in angiogenesis, lymphangiogenesis, and endothelial cell growth, playing a key role in stimulating cell proliferation, migration, and affecting vascular permeability. It may be involved in the formation of veins and lymphatic vasculature during embryogenesis, suggesting that it plays a key role in vascular development. VEGF-DD Protein, Human (HEK293, His) is the recombinant human-derived VEGF-DD protein, expressed by HEK293 , with C-6*His labeled tag. The total length of VEGF-DD Protein, Human (HEK293, His) is 109 a.a., with molecular weight of ~18.0 kDa.

HY-P72167

	DBI Protein, Mouse (His-Myc) DbiAcyl-CoA-binding protein; ACBP; DiazEPam-binding inhibitor; DBI; EndozEPine; EP	Mouse	E. coli
	DBI Protein, with high affinity, binds medium- and long-chain acyl-CoA esters, potentially acting as an intracellular carrier. Moreover, DBI displaces diazepam from the benzodiazepine (BZD) recognition site on the GABA type A receptor, suggesting a neuropeptide role in modulating GABA receptor action. Structurally, as a monomer, DBI underscores the importance of its individual unit in diverse molecular interactions within cellular pathways. DBI Protein, Mouse (His-Myc) is the recombinant mouse-derived DBI protein, expressed by E. coli , with N-10*His, C-Myc labeled tag. The total length of DBI Protein, Mouse (His-Myc) is 86 a.a., with molecular weight of ~16.9 kDa.

HY-P71615

	PDGF-DD Protein, Mouse (His-SUMO) Pdgfd; Scdgfb; Platelet-derived growth factor D; PDGF-D; Spinal cord-derived growth factor B; SCDGF-B	Mouse	E. coli
	PDGF-DD protein is an important growth factor that controls embryonic development, cell proliferation, migration, survival and chemotaxis, and has a potent mitogenic effect on mesenchymal cells. It plays a key role in wound healing and has carcinogenic potential, contributing to tumor formation. PDGF-DD Protein, Mouse (His-SUMO) is the recombinant mouse-derived PDGF-DD protein, expressed by E. coli , with N-His, N-SUMO labeled tag. The total length of PDGF-DD Protein, Mouse (His-SUMO) is 347 a.a., with molecular weight of ~66 kDa.

HY-P700186AF

	Animal-Free IL-1 alpha Protein, Mouse (His) Hematopoietin-1; Lymphocyte-Activating Factor (LAF); Endogenous Pyrogen (EP); Leukocyte	Mouse	E. coli
	IL-1 alpha protein is an important cytokine found intracellularly in non-hematopoietic cells that bridges innate and adaptive immunity. Binds to IL1R1 and IL1RAP to form a high-affinity receptor complex, initiates signaling through MYD88, IRAK1 or IRAK4, and activates the NF-kappa-B and MAPK pathways. Animal-Free IL-1 alpha Protein, Mouse (His) is the recombinant mouse-derived animal-FreeIL-1 alpha protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free IL-1 alpha Protein, Mouse (His) is 156 a.a., with molecular weight of ~18.93 kDa.

HY-P75520

	AKR1C2 Protein, Human (His) AKR-1C2; Aldo-keto reductase family 1 member C2; DD-2; AKR1C2	Human	E. coli
	AKR1C2 protein: Cytoplasmic aldehyde-keto reductase, which uses NADH and NADPH to reduce ketosteroids to hydroxysteroids. AKR1C2 Protein, Human (His) is the recombinant human-derived AKR1C2 protein, expressed by E. coli , with N-6*His labeled tag. The total length of AKR1C2 Protein, Human (His) is 323 a.a., with molecular weight of ~38 kDa.

HY-P74172

	EpCAM/TROP1 Protein, Rat (HEK293, His) EPithelial cell adhesion molecule; EP-CAM; EGP; KSA; CD326; TROP1	Rat	HEK293
	The EpCAM/TROP1 protein serves as a multifunctional molecule that promotes homogeneous interactions between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) in the mucosal epithelium. This suggests a crucial role in establishing an immune barrier against mucosal infection. EpCAM/TROP1 Protein, Rat (HEK293, His) is the recombinant rat-derived EpCAM/TROP1 protein, expressed by HEK293 , with C-His labeled tag. The total length of EpCAM/TROP1 Protein, Rat (HEK293, His) is 243 a.a., with molecular weight of 30-36 kDa.

HY-P74173

	EpCAM/TROP1 Protein, Rat (HEK293, Fc) EPithelial cell adhesion molecule; EP-CAM; EGP; KSA; CD326; TROP1	Rat	HEK293
	The EpCAM/TROP1 protein serves as a multifunctional molecule that promotes homogeneous interactions between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) in the mucosal epithelium. This suggests a crucial role in establishing an immune barrier against mucosal infection. EpCAM/TROP1 Protein, Rat (HEK293, Fc) is the recombinant rat-derived EpCAM/TROP1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of EpCAM/TROP1 Protein, Rat (HEK293, Fc) is 266 a.a., with molecular weight of ~61 & 37 kDa, respectively.

HY-P700037AF

	Animal-Free EpCAM/TROP1 Protein, Human (His) EPithelial cell adhesion molecule; EP-CAM; EGP; KSA; CD326; TROP1	Human	E. coli
	The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. Animal-Free EpCAM/TROP1 Protein, Human (His) is the recombinant human-derived animal-FreeEpCAM/TROP1 protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free EpCAM/TROP1 Protein, Human (His) is 242 a.a., with molecular weight of ~28.36 kDa.

HY-P702197

	ABCD3 Protein, Human (Cell-Free, His) ATP-binding cassette sub-family D member 3; 70 kDa peroxisomal membrane protein; PMP70	Human	E. coli Cell-free
	ABCD3 is a member of the ATP-binding cassette (ABC) family. ABCD3 Protein, Human (Cell-Free, His) is the recombinant human-derived ABCD3 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of ABCD3 Protein, Human (Cell-Free, His) is 659 a.a., with molecular weight of 81.5 kDa.

HY-P75736

	EpCAM/TROP1 Protein, Cynomolgus/Rhesus Macaque (HEK293) EPithelial cell adhesion molecule; EP-CAM; EGP; KSA; CD326; TROP2	Rhesus Macaque	HEK293
	EpCAM/TROP1 proteins play key roles in multiple processes as homogeneous interacting molecules that facilitate communication between mucosal epithelial midgut epithelial cells (IECs) and intraepithelial lymphocytes (IELs) to establish immunity against mucosal infections force. EpCAM/TROP1 Protein, Cynomolgus/Rhesus Macaque (HEK293) is the recombinant Rhesus Macaque-derived EpCAM/TROP1 protein, expressed by HEK293 , with tag free. The total length of EpCAM/TROP1 Protein, Cynomolgus/Rhesus Macaque (HEK293) is 265 a.a., with molecular weight of 35-45 kDa.

HY-P77531

	EpCAM/TROP1 Protein, Human (Biotinylated, HEK293, Fc) EPithelial cell adhesion molecule; EP-CAM; EGP; KSA; CD326; TROP1	Human	HEK293
	SHP-2 protein is a phosphatase enzyme that plays a crucial role in cell signaling. It is involved in regulating cellular processes such as cell growth, differentiation, and survival. Dysregulation of SHP-2 protein has been implicated in various diseases, including cancer and developmental disorders. Targeting SHP-2 protein offers potential therapeutic opportunities for these conditions. EpCAM/TROP1 Protein, Human (Biotinylated, HEK293, Fc) is the recombinant human-derived EpCAM/TROP1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of EpCAM/TROP1 Protein, Human (Biotinylated, HEK293, Fc) is 242 a.a., with molecular weight of ~54.1 KDa.

HY-P77532

	EpCAM/TROP1 Protein, Human (Biotinylated, HEK293, His) EPithelial cell adhesion molecule; EP-CAM; EGP; KSA; CD326; TROP1	Human	HEK293
	SHP-2 protein is a phosphatase enzyme that plays a crucial role in cell signaling. It is involved in regulating cellular processes such as cell growth, differentiation, and survival. Dysregulation of SHP-2 protein has been implicated in various diseases, including cancer and developmental disorders. Targeting SHP-2 protein offers potential therapeutic opportunities for these conditions. EpCAM/TROP1 Protein, Human (Biotinylated, HEK293, His) is the recombinant human-derived EpCAM/TROP1 protein, expressed by HEK293 , with C-10*His labeled tag. The total length of EpCAM/TROP1 Protein, Human (Biotinylated, HEK293, His) is 242 a.a., with molecular weight of ~29 KDa.

HY-P7621

	ABCB5 Protein, Human (Trx) rHuABCB5, N-Trx; ATP-binding cassette sub-family B member 5; P-glycoprotein ABCB5; ABCB5	Human	E. coli
	ABCB5, N-Trx Protein, Human is a plasma membrane-spanning protein that in humans is encoded by the ABCB5 gene. ABCB5 is an ABC transporter and P-glycoprotein family member principally expressed in physiological skin and human malignant melanoma.

HY-P72012

	ABCD1 Protein, Human (Cell-Free, His) ABC42; Abcd1; ABCD1_HUMAN; Adrenoleukodystrophy protein; ALD; Aldgh; ALDP; AMN; ATP binding cassette; sub family D ALD; ; member 1; ATP-binding cassette sub-family D member 1; OTTHUMP00000025960; OTTMUSP00000019283; RGD1562128; RP23 373N8.2; X linked adrenoleukodystrophy ALD; gene homolog	Human	E. coli Cell-free
	ABCD1, Human (His) is one of the four ATP-binding cassette (ABC) proteins in subfamily D. Dysfunction of ABCD1 causes neurodegenerative disorder X-linked adrenoleukodystrophy (X-ALD).

HY-P75737

	EpCAM/TROP1 Protein, Cynomolgus/Rhesus Macaque (HEK293, Fc) EPithelial cell adhesion molecule; EP-CAM; EGP; KSA; CD326; TROP3	Rhesus Macaque	HEK293
	EpCAM/TROP1 proteins play key roles in multiple processes as homogeneous interacting molecules that facilitate communication between mucosal epithelial midgut epithelial cells (IECs) and intraepithelial lymphocytes (IELs) to establish immunity against mucosal infections force. EpCAM/TROP1 Protein, Cynomolgus/Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived EpCAM/TROP1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of EpCAM/TROP1 Protein, Cynomolgus/Rhesus Macaque (HEK293, Fc) is 265 a.a., with molecular weight of ~58 kDa.

HY-P701958

	PBP1A Protein, Mycobacterium tuberculosis ponA1; Penicillin-binding protein 1A; PBP-1A; Penicillin-binding protein 1*; Penicillin-insensitive transglycosylase; PEPtidoglycan TGase; Penicillin-sensitive transpEPtidase; DD-transpEPtidase	Others	E. coli
	PBP1A (penicillin-binding protein 1A) is involved in cell wall formation and plays a crucial role in the synthesis of cross-linked peptidoglycan from lipid intermediates. The enzyme has a bifunctional structure. The penicillin-insensitive transglycosylase N-terminal domain is responsible for the formation of linear glycan chains, and the penicillin-sensitive transpeptidase C-terminal domain promotes the cross-linking of peptide subunits. PBP1A Protein, Mycobacterium tuberculosis is the recombinant PBP1A protein, expressed by E. coli , with tag free. The total length of PBP1A Protein, Mycobacterium tuberculosis is 430 a.a., .

HY-P702196

	ABCD2 Protein, Human (Cell-Free, His) ATP-binding cassette sub-family D member 2; Adrenoleukodystrophy-like 1; Adrenoleukodystrophy-related protein; hALDR	Human	E. coli Cell-free
	ABCD2 protein is an ATP-dependent transporter in the ABC family that promotes the transport of very long chain fatty acids (VLCFA)-CoA into peroxisomes and exhibits fatty acyl-CoA thioesterase (ACOT) and ATPase activities. Its substrate specificity overlaps with ABCD1, including a clear preference for shorter VLCFA (C22:0) and polyunsaturated fatty acids (PUFA) such as C22:6-CoA and C24:6-CoA. ABCD2 Protein, Human (Cell-Free, His) is the recombinant human-derived ABCD2 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of ABCD2 Protein, Human (Cell-Free, His) is 740 a.a., with molecular weight of 89.3 kDa.

HY-P701959

	PBP1A Protein, Mycobacterium tuberculosis (His) ponA1; Penicillin-binding protein 1A; PBP-1A; Penicillin-binding protein 1*; Penicillin-insensitive transglycosylase; PEPtidoglycan TGase; Penicillin-sensitive transpEPtidase; DD-transpEPtidase	Others	E. coli
	PBP1A (penicillin-binding protein 1A) is involved in cell wall formation and plays a crucial role in the synthesis of cross-linked peptidoglycan from lipid intermediates. The enzyme has a bifunctional structure. The penicillin-insensitive transglycosylase N-terminal domain is responsible for the formation of linear glycan chains, and the penicillin-sensitive transpeptidase C-terminal domain promotes the cross-linking of peptide subunits. PBP1A Protein, Mycobacterium tuberculosis (His) is the recombinant PBP1A protein, expressed by E. coli , with N-6*His labeled tag. The total length of PBP1A Protein, Mycobacterium tuberculosis (His) is 430 a.a., .

HY-P700095AF

	Animal-Free IL-1 alpha Protein, Human (His) Hematopoietin-1; Lymphocyte-Activating Factor (LAF); Endogenous Pyrogen (EP); IL1A; IL1F1	Human	E. coli
	IL-1 alpha protein is located in cells and is a key cytokine connecting innate immunity and adaptive immunity. After binding to IL1R1 through IL1RAP, it forms a high-affinity receptor complex, initiates a signaling cascade with adapter molecules such as MYD88, IRAK1 or IRAK4, and activates the NF-kappa-B and MAPK pathways. Animal-Free IL-1 alpha Protein, Human (His) is the recombinant human-derived animal-FreeIL-1 alpha protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free IL-1 alpha Protein, Human (His) is 159 a.a., with molecular weight of ~18.99 kDa.

HY-P700627

	DBI Protein, Mouse (P. pastoris, His) Dbi; diazEPam binding inhibitor; EP; Acbp; ACBD1; endozEPine; acyl-CoA-binding protein; diazEPam binding inhibitor, splice form 1b	Mouse	P. pastoris
	DBI Protein, with high affinity, binds medium- and long-chain acyl-CoA esters, potentially acting as an intracellular carrier. Moreover, DBI displaces diazepam from the benzodiazepine (BZD) recognition site on the GABA type A receptor, suggesting a neuropeptide role in modulating GABA receptor action. Structurally, as a monomer, DBI underscores the importance of its individual unit in diverse molecular interactions within cellular pathways. DBI Protein, Mouse (P. pastoris, His) is the recombinant mouse-derived DBI protein, expressed by P. pastoris, with N-6*His labeled tag. The total length of DBI Protein, Mouse (P. pastoris, His) is 86 a.a., with molecular weight of 11.9 kDa.

HY-P702195

	ABCB8 Protein, Human (Cell-Free, His, SUMO) Mitochondrial potassium channel ATP-binding subunit; ATP-binding cassette sub-family B member 8, mitochondrial; ABCB8; Mitochondrial ATP-binding cassette 1; M-ABC1; Mitochondrial sulfonylurea-recEPtor; MITOSUR	Human	E. coli Cell-free
	ABCB8 is the ATP-binding subunit of mitochondrial potassium channels and cooperates with CCDC51/MITOK to form mitoK (ATP) channels in the inner mitochondrial membrane. This complex promotes ATP-dependent potassium currents. ABCB8 Protein, Human (Cell-Free, His, SUMO) is the recombinant human-derived ABCB8 protein, expressed by E. coli Cell-free , with N-6*His, N-SUMO labeled tag. The total length of ABCB8 Protein, Human (Cell-Free, His, SUMO) is 656 a.a., with molecular weight of 87 kDa.

HY-P72069

	ABCC1 Protein, Human (His) ABC 29; ABC29; ABCC 1; ABCC; Abcc1; ATP binding cassette sub family C CFTR/MRP; member 1; ATP binding cassette sub-family C member 1; ATP binding cassette subfamily C member 1; ATP binding cassette transporter variant ABCC1delta ex13; ATP binding cassette transporter variant ABCC1delta ex13&14; ATP binding cassette transporter variant ABCC1delta ex25; ATP binding cassette transporter variant ABCC1delta ex25&26; ATP binding cassette, sub-family C CFTR/MRP; , member 1; ATP-binding cassette sub-family C member 1; DKFZp686N04233; DKFZp781G125; GS X; GSX; Leukotriene C4; transporter; LTC4 transporter; MRP 1; MRP; MRP1; MRP1_HUMAN; Multidrug resistance associated protein 1; Multidrug resistance protein; Multidrug resistance-associated protein 1; Multiple drug resistance associated protein; Multiple drug resistance protein 1	Human	E. coli
	ABCC1, Human (His) is a multitasking ATP-binding cassette (ABC) transporter. ABCC1, Human plays a part in inflammatory and other immunological diseases, age-related macular degeneration, cardiovascular disease, and certain neurological disorders as well as tumor progression.

HY-P701354

	ABCC4 Protein, Human (HEK293, GFP, Strep, His) ABCC4; ATP-binding cassette sub-family C member 4; MRP/cMOAT-related ABC transporter; Multi-specific organic anion transporter B; MOAT-B; Multidrug resistance-associated protein 4	Human	HEK293
	ABCC4 Protein, an ATP-binding cassette (ABC) family member, actively transports endogenous compounds (cAMP, cGMP, bile acids) and xenobiotics from cells. Its versatility extends to glutathione conjugates (LTC4, LTB4) and drug metabolites, mediating cotransport of bile acids with reduced glutathione. ABCC4's function includes resistance to anticancer agents like methotrexate, highlighting its role in cellular communication and drug transport. ABCC4 Protein, Human (HEK293, GFP, Strep, His) is the recombinant human-derived ABCC4 protein, expressed by HEK293 , with C-10*His, C-GFP, C-Strep labeled tag. The total length of ABCC4 Protein, Human (HEK293, GFP, Strep, His) is 1325 a.a., .

HY-P701355

	bABCC1 Protein, Human (HEK293, GFP, Strep, His) ABCC1; Multidrug resistance-associated protein 1; ATP-binding cassette sub-family C member 1; Glutathione-S-conjugate-translocating ATPase ABCC1; Leukotriene C(4) transporter; LTC4 transporter	Human	HEK293
	The bABCC1 protein plays a key role in cellular physiology, mediating the ATP-dependent export of a variety of substrates, including drugs and organic anions. Notably, it confers resistance to anticancer drugs, actively reducing their intracellular accumulation. bABCC1 Protein, Human (HEK293, GFP, Strep, His) is the recombinant human-derived bABCC1 protein, expressed by HEK293 , with C-10*His, C-GFP, C-Strep labeled tag. The total length of bABCC1 Protein, Human (HEK293, GFP, Strep, His) is 1530 a.a., .

HY-P701356

	bABCC1 Protein, Human (HEK293, E1454Q, GFP, Strep, His) ABCC1; Multidrug resistance-associated protein 1; ATP-binding cassette sub-family C member 1; Glutathione-S-conjugate-translocating ATPase ABCC1; Leukotriene C(4) transporter; LTC4 transporter	Human	HEK293
	The bABCC1 protein plays a key role in cellular physiology, mediating the ATP-dependent export of a variety of substrates, including drugs and organic anions. Notably, it confers resistance to anticancer drugs, actively reducing their intracellular accumulation. bABCC1 Protein, Human (HEK293, E1454Q, GFP, Strep, His) is the recombinant human-derived bABCC1 protein, expressed by HEK293 , with C-10*His, C-GFP, C-Strep labeled tag and E1454Q, , , , mutation. The total length of bABCC1 Protein, Human (HEK293, E1454Q, GFP, Strep, His) is 1530 a.a., .

HY-P70154

	EpCAM/TROP1 Protein, Human (HEK293, His) 1 Publications Verification rHuEPithelial cell adhesion molecule/EPCAM, His; EPithelial Cell Adhesion Molecule; EP-CAM; Adenocarcinoma-Associated Antigen; Cell Surface Glycoprotein Trop-1; EPithelial Cell Surface Antigen; EPithelial Glycoprotein; EGP; EPithelial Glycoprotein 314; EGP314; hEGP314; KSA; Tumor-Associated Calcium Signa	Human	HEK293
	The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (HEK293, His) is the recombinant human-derived EpCAM/TROP1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of EpCAM/TROP1 Protein, Human (HEK293, His) is 242 a.a., with molecular weight of approximately 34-42 kDa.

HY-P70155

	EpCAM/TROP1 Protein, Human (HEK293, Fc) rHuEPithelial cell adhesion molecule/EPCAM, Fc ; EPithelial Cell Adhesion Molecule; EP-CAM; Adenocarcinoma-Associated Antigen; Cell Surface Glycoprotein Trop-1; EPithelial Cell Surface Antigen; EPithelial Glycoprotein 314; EGP314; Major Gastrointestinal Tumor-Associated Protein GA733-2; Tumor-Associated	Human	HEK293
	The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (HEK293, Fc) is the recombinant human-derived EpCAM/TROP1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of EpCAM/TROP1 Protein, Human (HEK293, Fc) is 242 a.a., with molecular weight of 60-80 kDa.

HY-P72201

	GAPDH Protein, Human (His-SUMO) G3P_HUMAN; G3PD; G3PDH; GAPD; GAPDH; Glyceraldehyde 3 phosphate dehydrogenase; glyceraldehyde 3-PDH; Glyceraldehyde-3-phosphate dehydrogenase; HEL-S-162EP; KNC-NDS6; MGC102544; OCAS; p38 component; OCT1 coactivator in S phase; 38-KD component; pEPtidyl cysteine S nitrosylase GAPDH	Human	E. coli
	GAPDH, a multifunctional protein, acts as a key enzyme in glycolysis, catalyzing the conversion of G3P. It also functions as a nitrosylase, impacting nuclear processes. In addition, it influences cytoskeleton organization, associates with CHP1, participates in transcript-selective translation inhibition, contributes to immune responses, and mediates nuclear events through S-nitrosylation of target proteins. GAPDH Protein, Human (His-SUMO) is the recombinant human-derived GAPDH protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag. The total length of GAPDH Protein, Human (His-SUMO) is 334 a.a., with molecular weight of ~51.9 kDa.

HY-P72166

	DBI Protein, Human (103a.a, His) ACBD1; ACBP; ACBP_HUMAN; Acyl CoA binding domain containing 1; Acyl CoA binding protein; Acyl Coenzyme A binding domain containing 1; Acyl coenzyme A binding protein; Acyl-CoA-binding protein; CCK RP; CCKRP; Cholecystokinin releasing pEPtide trypsin sensitive; DBI; DiazEPam-binding inhibitor; EndozEPine; EP; GABA recEPtor modulator; MGC70414	Human	E. coli
	DBI, a versatile protein, binds medium- and long-chain acyl-CoA esters, indicating a potential intracellular carrier role. It also displaces diazepam from the benzodiazepine recognition site on the GABA type A receptor. This dual functionality suggests DBI may act as a neuropeptide, modulating GABA receptor activity. Remarkably, DBI functions as a monomer in these interactions. DBI Protein, Human (103a.a, His) is the recombinant human-derived DBI protein, expressed by E. coli , with N-6*His labeled tag. The total length of DBI Protein, Human (103a.a, His) is 103 a.a., with molecular weight of ~14 kDa.

HY-P72183

	EpCAM/TROP1 Protein, Human (His-SUMO) 17 1A; 323/A3; Adenocarcinoma associated antigen; Adenocarcinoma-associated antigen; Antigen identified by monoclonal AUA1; AUA1; CD326; CD326 antigen; Cell surface glycoprotein Trop 1; Cell surface glycoprotein Trop 2; Cell surface glycoprotein Trop-1; CO 17A; CO17 1A; CO17A; DIAR5; EGP 2; EGP; EGP2; EGP314; EGP40; EP CAM; EP-CAM; EPCAM; EPCAM_HUMAN; EPCAM1; EPithelial cell adhesion molecule; EPithelial Cell Adhesion Molecule Intracellular Domain EPCAM-ICD; ; EPithelial cell surface antigen; EPithelial cellular adhesion molecule; EPithelial glycoprotein 1; EPithelial glycoprotein 314; EPithelial glycoprotein; ESA; GA733 1; GA733 2; GA733-2; gastrointestinal tumor-associated antigen 2; 35-KD glycoprotein; gp4; hEGP 2; hEGP314; HNPCC8; Human EPithelial glycoprotein 2; KS 1/4 antigen; KS1/4; KSA; Ly74; Lymphocyte antigen 74; M1S 1; M1S2; M4S1; Major gastrointestinal tumor associated protein GA733 2; Major gastrointestinal tumor-associated protein GA733-2; mEGP314; Membrane component chro	Human	E. coli
	The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag. The total length of EpCAM/TROP1 Protein, Human (His-SUMO) is 242 a.a., with molecular weight of ~40.4 kDa.

Cat. No.	Product Name	Chemical Structure

HY-143941S

Hydroxychloroquine EP impurity D-d5 dihydrochloride

Hydroxychloroquine EP impurity D-d₅ (dihydrochloride) is the deuterium labeled Hydroxychloroquine EP impurity D dihydrochloride[1].
HY-142592S

Clozapine EP impurity D-d8

Clozapine EP impurity D-d₈ is the deuterium labeled Clozapine EP impurity D[1].
HY-144242S

Voriconazole EP impurity D-d3

Voriconazole EP impurity D-d₃ is the deuterium labeled Voriconazole EP impurity D[1].

HY-Z1430S

(3R,4S)-Paroxetine-d4 hydrochloride
Paroxetine EP impurity D-d₄ (hydrochloride) is deuterium labeled (3R,4S)-3-((benzo[d][1,3]dioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine (Paroxetine Impurity）.

HY-143907S

Atorvastatin EP impurity H-d5

Atorvastatin EP impurity H-d₅ is the deuterium labeled Atorvastatin EP impurity H[1].
HY-143990S

Modafinil EP impurity B-d5

Modafinil EP impurity B-d₅ is the deuterium labeled Modafinil EP impurity B[1].
HY-143982S

Mianserin EP impurity E-d4 hydrochloride

Mianserin EP impurity E-d₄ (hydrochloride) is the deuterium labeled Mianserin EP impurity E hydrochloride[1].
HY-144203S

Trospium EP impurity C-d8 chloride

Trospium EP impurity C-d₈ (chloride) is the deuterium labeled Trospium EP impurity C chloride[1].
HY-W069504S2

Propan-1-amine-d5 hydrochloride

Propan-1-amine-dd₅ hydrochloride is the deuterium labeled Propan-1-amine hydrochloride[1].
HY-143997S

(Rac)-Nicotine EP impurity A-d4 hydrochloride

(Rac)-Nicotine EP impurity A-d₄ (hydrochloride) is the deuterium labeled (Rac)-Nicotine EP impurity A hydrochloride[1].
HY-144221S

Tiotropium bromide EP impurity A-d6

Tiotropium bromide EP impurity A-d₆ is the deuterium labeled Tiotropium bromide EP impurity A[1].
HY-13204S2

rel-Biperiden EP impurity A-d5

rel-Biperiden EP impurity A-d₅ is deuterium labeled Biperiden (hydrochloride).
HY-13204S3

rel-Biperiden EP impurity B-d5

rel-Biperiden EP impurity B-d₅ is deuterium labeled Biperiden (hydrochloride).
HY-W336012S

Metoprolol EP impurity O-d7 hydrochloride

Metoprolol EP impurity O-d₇ (hydrochloride) is the deuterium labeled 3,3'-(Isopropylazanediyl)bis(1-(4-(2-methoxyethyl)phenoxy)propan-2-ol)[1].

HY-W031727S1

Hydroxychloroquine-d5
Hydroxychloroquine-d₅ is the deuterium labeled Hydroxychloroquine[1]. Hydroxychloroquine is a synthetic antimalarial agent which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Hydroxychloroquine is efficiently inhibits SARS-CoV-2 infection in vitro[2][3][4].

HY-W099680S1

Hexyltriphenylphosphonium-d5 bromide

Hexyltriphenylphosphonium-dd₅ bromide is the deuterium labeled Hexyltriphenylphosphonium bromide[1].

HY-W031727S

Hydroxychloroquine-d4-1 sulfate
Hydroxychloroquine-d₄-1 (sulfate) is the deuterium labeled Hydroxychloroquine. Hydroxychloroquine is a synthetic antimalarial agent which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Hydroxychloroquine is efficiently inhibits SARS-CoV-2 infection in vitro[1][2][3].

HY-B1370S

Hydroxychloroquine-d4 sulfate
Hydroxychloroquine-d₄ (sulfate) is the deuterium labeled Hydroxychloroquine sulfate. Hydroxychloroquine sulfate (HCQ sulfate) is a synthetic antimalarial agent which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Hydroxychloroquine sulfate is efficiently inhibits SARS-CoV-2 infection in vitro[1][2][3].

HY-10820AS

Pemetrexed-d5 disodium
Pemetrexed-d₅ (disodium) is the deuterium labeled Pemetrexed disodium. Pemetrexed disodium (LY231514 disodium) is an antifolate, the Kis of the pentaglutamate of Pemetrexed disodium are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively[1].

HY-50898S1

Lapatinib-d7 dihydrochloride
Lapatinib-d₇ (dihydrochloride) is the deuterium labeled Lapatinib dihydrochloride. Lapatinib (GW572016) dihydrochloride is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively[1].

HY-15581S

MMAD-d8

MMAD-d₈D is a deuterated form of MMAD, which is a microtubule disrupting agent.

HY-B0131S2

Prostaglandin E1-d9
Prostaglandin E1-d₉ is deuterium labeled Prostaglandin E1.Prostaglandin E1 is a prostanoid receptor ligand, with Kis of 1.1 nM, 2.1 nM, 10 nM, 33 nM and 36 nM for mouse EP3, EP4, EP2, IP and EP1, respectively. Prostaglandin E1 induces vasodilation and inh

HY-150660S

Ercalcidiol-13C5

25-Hydroxyvitamin D2-(20,21,22,26,27- ¹³C₅) solution is the ¹³C labeled 25-Hydroxyvitamin D2[1].

HY-136540S

Resolvin D3-d5
Resolvin D3-d₅ is the deuterium labeled Resolvin D3. Resolvin D3 (RvD3) is a docosahexaenoic acid (DHA) derived mediator. Resolvin D3 is dysregulated in arthritis and reduces arthritic inflammation[1][2].

HY-75958S1

Vitamin D4-d5
Vitamin D4-d₅ is the deuterium labeled Vitamin D4. Vitamin D4 (22-Dihydroergocalciferol) is a Vitamin D derived from fungi. The precursor of Vitamin D4 is 22,23-dihydroergosterol[1].

HY-B0184S1

Felbamate-d5
Felbamate-d₅ is the deuterium labeled Felbamate[1]. Felbamate (W-554) is a potent nonsedative anticonvulsant whose clinical effect may be related to the inhibition of N-methyl-D-aspartate (NMDA)[2][3].

HY-150663S

Calcitriol-13C5

1α,25-Dihydroxyvitamin D3-(23,24,25,26,27- ¹³C₅) solution is the ¹³C labeled 1α,25-Dihydroxyvitamin D3[1].

HY-16560S

Camptothecin-d5

Camptothecin-d₅ is the deuterium labeled Camptothecin. Camptothecin (CPT), a kind of alkaloid, is a DNA topoisomerase I (Topo I) inhibitor with an IC50 of 679 nM[1]. Camptothecin (CPT) exhibits powerful antineoplastic activity against colorectal, breast, lung and ovarian cancers, modulates hypoxia-inducible factor-1α (HIF-1α) activity by changing microRNAs (miRNA) expression patterns in human cancer cells[2][3].

HY-B0715S2

Pentoxifylline-d5

Pentoxifylline-d₅ is the deuterium labeled Pentoxifylline. Pentoxifylline (BL-191), a haemorheological agent, is an orally active non-selective phosphodiesterase (PDE) inhibitor, with immune modulation, anti-inflammatory, hemorheological, anti-fibrinolytic and anti-proliferation effects. Pentoxifylline can be used for the research of peripheral vascular disease, cerebrovascular disease and a number of other conditions involving a defective regional microcirculation[1][2][3].

HY-107819S

5α-Cholestan-3β-ol-d5

5α-Cholestan-3β-ol-d₅ is the deuterium labeled 5α-Cholestan-3β-ol. 5α-Cholestan-3β-ol is a derivitized steroid compound[1].

HY-N0573S

Umbelliferone-d5
Umbelliferone-d₅ is the deuterium labeled Umbelliferone. Umbelliferone (7-Hydroxycoumarin), a natural product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent.

HY-W022036S

2-Ethoxyphenol-d5

2-Ethoxyphenol-d₅ is the deuterium labeled 2-Ethoxyphenol[1].
HY-66005S5

Acetaminophen-d5

Acetaminophen-d₅ is deuterated-labeled Acetaminophen.

HY-121636S

Resolvin D2-d5
Resolvin D2-d₅ is the deuterium labeled Resolvin D2. Resolvin D2 is a metabolite of docosahexaenoic acid (DHA), with anti-inflammatory, anti-infective activities. Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis. Resolvin D2 is a remarkably potent inhibitor of TRPV1 (IC50 = 0.1 nM) and TRPA1 (IC50 = 2 nM) in primary sensory neurons[1][2][3].

HY-B1207S

Urethane-d5
Urethane-d₅ is the deuterium labeled Urethane. Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial, protozoal, sea urchin egg, and plant tissue growth in vitro[1].

HY-77839S

Cortodoxone-d5

Cortodoxone-d₅ is the deuterium labeled Cortodoxone.

HY-14814S

Delafloxacin-d5
Delafloxacin-d₅ is deuterium labeled Delafloxacin. Delafloxacin (RX-3341; WQ-3034; ABT492) is a broad-spectrum fluoroquinolone antibiotic. Delafloxacin has a broad spectrum of activity that includes drug-resistant Staphylococcus aureus, Streptococcus pneumoniae, and Klebsiella pneumonia[1].

HY-13636S1

Fulvestrant-d5

Fulvestrant-d5 is a isotope of Fulvestrant .

HY-125527S

Resolvin D1-d5

Resolvin D1-d₅ is the deuterium labeled Resolvin D1. Resolvin D1 (RvD1), an endogenous pro-resolving mediator of inflammation, is derived from omega-3 docosahexaenoic acid during the resolution phase of acute inflammation. Resolvin D1 blocks proinflammatory neutrophil migration by regulating actin polymerization, reduces TNF-α–mediated inflammation in macrophages, and enhances phagocytosis of apoptotic cells by macrophages[1][2].

HY-B0200S

Cephalexin-d5
Cephalexin-d₅ is deuterium labeled Cephalexin. Cephalexin (Cefalexin; Cephacillin) is a potent, orally active and the first-generation cephalosporin antibiotic. Cephalexin kills gram-positive and some gram-negative bacteria by disrupting the growth of the bacterial cell wall. Cephalexin monohydrate is used for the research of pneumonia, strep throat, and bacterial endocarditis, et al[1].

HY-B0178AS1

Guanidine-d5 hydrochloride
Guanidine-d₅ (hydrochloride) is the deuterium labeled Guanidine hydrochloride[1]. Guanidine hydrochloride (Guanidinium chloride) a strong chaotrope, is also a strong denaturant of proteins[2][3].

HY-N0570S1

Hydroxytyrosol-d5
Hydroxytyrosol-d₅ is the deuterium labeled Hydroxytyrosol. Hydroxytyrosol (DOPET) is a phenolic compound drawn from the olive tree and its leaves with anti-oxidant, anti-atherogenic, anti-thrombotic, antimicrobial, anti-inflammatory and anti-tumour effects[1][2].

HY-B0941S

6-Benzylaminopurine-d5

6-Benzylaminopurine-d₅ is the deuterium labeled 6-Benzylaminopurine. 6-Benzylaminopurine is a cytokinin[1].
HY-B0878S

Halobetasol propionate-d5

Halobetasol propionate-d₅ is deuterium labeled Halobetasol (propionate).

HY-B1290S2

2-Phenylethanol-d5

2-Phenylethanol-d₅ is the deuterium labeled 2-Phenylethanol[1]. 2-Phenylethanol (Phenethyl alcohol), extracted from rose, carnation, hyacinth, Aleppo pine, orange blossom and other organisms, is a colourless liquid. It has a pleasant floral odor and also an autoantibiotic produced by the fungus Candida albicans[2]. It is used as an additive in cigarettes and also used as a preservative in soaps due to its stability in basic conditions.

HY-160261S

EP300/CBP-IN-2

EP300/CBP-IN-2 is a potent EP300/CBP inhibitor that has good activity in vivo. EP300/CBP-IN-2 can be used for the research of cancer .

HY-18600AS

Azimilide-d8 dihydrochloride
Azimilide-d₈ (dihydrochloride) is the deuterium labeled Azimilide dihydrochloride. Azimilide Dihydrochloride (NE-10064 Dihydrochloride) is a class III antiarrhythmic compound, inhibits I(Ks) and I(Kr) in guinea-pig cardiac myocytes and I(Ks) (minK) channels expressed in Xenopus oocytes.

HY-B0346S

Propylthiouracil-d5

Propylthiouracil-d₅ is the deuterium labeled Propylthiouracil. Propylthiouracil (6-Propyl-2-thiouracil) is a thyroperoxidase and 5'-deiodinase inhibitor.

HY-12222S

Obeticholic acid-d5
Obeticholic acid-d₅ is the deuterium labeled Obeticholic acid. Obeticholic acid (INT-747) is a potent, selective and orally active FXR agonist with an EC50 of 99 nM. Obeticholic acid has anticholeretic and anti-inflammation effect. Obeticholic acid also induces autophagy[1][2][3].

HY-12760S

Indoramin-d5

Indoramin-d₅ is deuterium labeled Indoramin, which is a piperidine antiadrenergic agent.

Cat. No.	Product Name	Application	Reactivity

HY-P83597

Prostaglandin E Receptor EP2 Antibody (YA3342) EP2; PGE2 recEPtor EP2 subtype; Prostaglandin E recEPtor 2 subtype EP2 53kDa; Prostaglandin E2 recEPtor EP2 subtype; Prostanoid EP2 recEPtor; Ptger2	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat, Cow

HY-P80075

CDC42EP1 Antibody	WB	Human
CDC42EP1 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 40 kDa, targeting to CDC42EP1. It can be used for WB assays with tag free, in the background of Human.

HY-P80954

GAPDH Antibody (YA848) G3PD; GAPD; HEL-S-162EP	WB	Human, Monkey, Rat, Mouse, Saccharomyces cerevisiae, Pichia pastoris, Hamster
GAPDH Antibody (YA848) is a non-conjugated and Mouse origined monoclonal antibody about 36 kDa. It can be used for WB assays with tag free, in the background of Human, Monkey, Rat, Mouse, Hamster, Saccharomyces cerevisiae, Pichia pastoris.

HY-P82885

EDD Antibody (YA2630)

DD5; EDD; EDD1; hHYD; HYD; Rat100; Ubiquitin protein ligase; UBR5
WB Human, Mouse
HY-P82593

AKR1C3 Antibody (YA2338)

DD3; DDX; HA1753; HAKRB; HAKRe; HSD17B5; KIAA0119; hluPGFS
WB, ICC/IF, IP, FC Human

HY-P80665

F4/80 Antibody Emr1; Ly71; Gpf480; TM7LN3; DD7A5-7; EGF-TM7	IHC-P, ICC/IF, FC	Mouse
F4/80 Antibody is a non-conjugated and Rat origined monoclonal antibody, targeting to F4/80. It can be used for IHC-P,ICC/IF,FC assays with tag free, in the background of Mouse.

HY-P80775

p300 Antibody EP300; P300; Histone acetyltransferase p300; p300 HAT; E1A-associated protein p300	ICC/IF, WB, IHC-F, IHC-P, ELISA	Human, Mouse, Rat
p300 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 264 kDa, targeting to p300. It can be used for ICC/IF,WB,IHC-F,IHC-P,ELISA assays with tag free, in the background of Human, Mouse, Rat.

HY-P80527

ABCB5 Antibody (YA836) ABCB5 P-gp; ATP binding cassette sub family B (MDR/TAP) member 5; P glycoprotein ABCB5	WB, ICC/IF	Human
ABCB5 Antibody (YA836) is a non-conjugated and Mouse origined monoclonal antibody about 139 kDa, targeting to ABCB5 (8D2). It can be used for WB,ICC/IF assays with tag free, in the background of Human.

HY-P80772

P Glycoprotein Antibody p-pg; ABCB1; MDR1; PGY1; Multidrug resistance protein 1; ATP-binding cassette sub-family B member 1; P-glycoprotein 1; CD antigen CD243	WB	Human
P Glycoprotein Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 141 kDa, targeting to P Glycoprotein. It can be used for WB assays with tag free, in the background of Human.

HY-P81118

MRP2/ABCC2 Antibody multidrug resistance-associated protein2; ABC30; ABCC2; ATP binding cassette sub family C (CFTR/MRP) member 2; ATP binding cassette subfamily C member 2; Canalicular multidrug resistance protein; Canalicular multispecific organic anion transporter 1; CMOAT; CMOAT1; cMRP; DJS; KIAA1010; MRP 2; MRP-2; MRP2; Multidrug resistance associated protein 2; MRP2_HUMAN; ATP-binding cassette sub-family C member 2; Multidrug resistance-associated protein 2.	WB; ELISA; IHC-P; IHC-F; IF	Human, Mouse, Rat,
MRP2/ABCC2 Antibody is an unconjugated, approximately 174 kDa, rabbit-derived, anti-MRP2/ABCC2 polyclonal antibody. MRP2/ABCC2 Antibody can be used for: WB, ELISA, IHC-P, IHC-F, IF expriments in human, mouse, rat, background without labeling.

HY-P83341

Mucin 1 Antibody (YA3086) MUC1; PUM; Mucin-1; MUC-1; Breast carcinoma-associated antigen DF3; Carcinoma-associated mucin; EPisialin; H23AG; Krebs von den Lungen-6; KL-6; PEMT; Peanut-reactive urinary mucin; PUM; Polymorphic EPithelial mucin; PEM; Tumor-associated EP	WB, IHC-P, ICC/IF, IP, FC	Human

HY-P81220

ADGRE1 Antibody F4/80; Adhesion G protein-coupled recEPtor E1; Cell surface glycoprotein EMR1; Cell surface glycoprotein F4/80; DD7A5 7; Egf like module containing mucin like hormone recEPtor like 1; Egf like module containing mucin like hormone recEPtor like sequence 1; EGF like module recEPtor 1; EGF TM7; EGF-like module recEPtor 1; EGF-like module-containing mucin-like hormone recEPtor-like 1; EGFTM7; EMR 1; EMR1; EMR-1; EMR1 hormone recEPtor; EMR1_HUMAN; AGRE1_HUMAN; Gpf480; Ly71; Lymphocyte antigen 71; TM7LN3.	WB; ELISA; Flow-Cyt	Human, Mouse(predicted: Rat, Pig, Guinea Pig)
ADGRE1 Antibody is an unconjugated, approximately 95 kDa, rabbit-derived, anti-ADGRE1 polyclonal antibody. ADGRE1 Antibody can be used for: WB, ELISA, Flow-Cyt expriments in human, mouse, and predicted: rat, pig, guinea pig background without labeling.

HY-P80657

EpCAM Antibody (YA458) EPCAM; GA733-2; M1S2; M4S1; MIC18; TACSTD1; TROP1; EPithelial cell adhesion molecule; EP-CAM; Adenocarcinoma-associated antigen; Cell surface glycoprotein Trop-1; EPithelial cell surface antigen; EPithelial glycoprotein; EGP; EPithelial glycoprotein 314;	WB, IHC-F, IHC-P, ICC/IF, IP	Human
EpCAM Antibody (YA458) is a non-conjugated and Rabbit origined monoclonal antibody about 35 kDa, targeting to EpCAM. It can be used for WB,IHC-F,IHC-P,ICC/IF,IP assays with tag free, in the background of Human.

HY-P81083

ADGRE1 (F4/80) Antibody (YA920) F4/80 (mouse); Adhesion G protein-coupled recEPtor E1; Cell surface glycoprotein EMR1; Cell surface glycoprotein F4/80; DD7A5 7; Egf like module containing mucin like hormone recEPtor like 1; Egf like module containing mucin like hormone recEPtor like sequence 1; EGF like module recEPtor 1; EGF TM7; EGF-like module recEPtor 1; EGF-like module-containing mucin-like hormone recEPtor-like 1; EGFTM7; EMR 1; EMR1; EMR-1; EMR1 hormone recEPtor; EMR1_HUMAN; AGRE1_HUMAN; Gpf480; Ly71; Lymphocyte antigen 71; TM7LN3.	WB; IP	Human(predicted: Mouse, Rat)
ADGRE1 (F4/80) Antibody (YA920) is an unconjugated, approximately 95 kDa, mouse-derived, anti-ADGRE1 (F4/80) (YA920) monoclonal antibody. ADGRE1 (F4/80) Antibody (YA920) can be used for: WB, IP expriments in human, and predicted: mouse, rat background without labeling.

Cat. No.	Product Name		Classification

HY-B0216S

Ethynyl Estradiol-d4 17α-Ethynylestradiol-d<sub>4sub>; Ethynylestradiol-d<sub>4sub>		Alkynes
Ethynyl Estradiol-d₄ is the deuterium labeled Ethynyl Estradiol. Ethynyl Estradiol (17α-Ethynylestradiol;Ethynylestradiol) is an orally bio-active estrogen used in almost all modern formulations of combined oral contraceptive pills. Ethynyl Estradiol-d4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-G0018S

Norgestimate metabolite norelgestromin-d6 17-Deacetyl norgestimate-d<sub>6sub>; 17-Deacylnorgestimate-d<sub>6sub>		Alkynes
Norgestimate metabolite norelgestromin-d₆ is the deuterium labeled Norgestimate metabolite norelgestromin. Norelgestromin is a metabolite of Norgestimate, which is a progestin or synthetic progestogen. Norgestimate metabolite norelgestromin-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-17413S

Zidovudine-d3 Azidothymidine-d<sub>3sub>; AZT-d<sub>3sub>; ZDV-d<sub>3sub>		Azide
Zidovudine-d₃ is the deuterium labeled Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection. Zidovudine increases CRISPR/Cas9-mediated editing frequency. Zidovudine-d3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

HY-50896S

Erlotinib-d6 CP-358774-d<sub>6sub>; NSC 718781-d<sub>6sub>; OSI-774-d<sub>6sub>		Alkynes
Erlotinib-d₆ (CP-358774 D6) is a deuterium labeled Erlotinib (CP-358774). Erlotinib is a directly acting inhibitor EGFR tyrosine kinase inhibitor with an IC50 of 2 nM for human EGFR[1]. Erlotinib-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B0110S

Gestodene-d6 SHB 331-d<sub>6sub>; WL 70-d<sub>6sub>		Alkynes
Gestodene-d₆is the deuterium labeled Gestodene. Gestodene(SHB 331) is a progestogen hormonal contraceptive[1][2]. Gestodene-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-50896S1

Erlotinib-13C6 CP-358774-¹³C<sub>6sub>; NSC 718781-¹³C<sub>6sub>; OSI-774-¹³C<sub>6sub>		Alkynes
Erlotinib- ¹³C₆ is a ¹³C-labeled Erlotinib. Erlotinib is a directly acting EGFR tyrosine kinase inhibitor, with an IC50 of 2 nM for human EGFR[1].

HY-12008S1

Erlotinib-13C6 hydrochloride CP-358774-¹³C<sub>6sub> hydrochloride; NSC 718781-¹³C<sub>6sub> hydrochloride; OSI-774-¹³C<sub>6sub> hydrochloride		Alkynes
Erlotinib- ¹³C₆ (hydrochloride) is the ¹³C labeled Erlotinib Hydrochloride[1]. Erlotinib Hydrochloride (CP-358774 Hydrochloride) inhibits purified EGFR kinase with an IC50 of 2 nM[2]. Erlotinib-13C6 (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-17413S1

Zidovudine-13C,d3 Azidothymidine-¹³C,d<sub>3sub>; AZT-¹³C,d<sub>3sub>; ZDV-¹³C,d<sub>3sub>		Azide
Zidovudine- ¹³C,d₃ is the ¹³C- and deuterium labeled Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection. Zidovudine increases CRISPR/Cas9-mediated editing frequency. Zidovudine-13C,d3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

HY-B0554S

Norethindrone-d6 Norethisterone-d<sub>6sub>		Alkynes
Norethindrone-d₆ is the deuterium labeled Norethindrone. Norethindrone is a female progestin approved by FDA for the treatment of endometriosis, uterine bleeding caused by abnormal hormone levels, and secondary amenorrhea. Norethindrone-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B0257S

Levonorgestrel-d8 D-Norgestrel-d<sub>8sub>		Alkynes
Levonorgestrel-d₈ is the deuterium labeled Levonorgestrel. Levonorgestrel is a synthetic progestogen used as an active ingredient in some hormonal contraceptives[1][2]. Levonorgestrel-d8 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B0216S2

Ethynyl Estradiol-13C2 17α-Ethynylestradiol-¹³C<sub>2sub>; Ethynylestradiol-¹³C<sub>2sub>		Alkynes
Ethynyl Estradiol- ¹³C₂ is the ¹³C-labeled Ethynyl Estradiol. Ethynyl Estradiol-13C2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-14605BS

Rasagiline-13C3 mesylate racemic AGN1135-¹³C<sub>3sub>; TVP1012-¹³C<sub>3sub> racemic		Alkynes
Rasagiline- ¹³C₃ (mesylate racemic) is a ¹³C-labeled Rasagiline mesylate racemic. Rasagiline mesylate racemic is a highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor[1]. Rasagiline-13C3 (mesylate racemic) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B1710S

Norethindrone acetate-d8 19-Norethindrone acetate-d<sub>8sub>		Alkynes
Norethindrone acetate-d₈ is the deuterium labeled Norethindrone acetate. Norethindrone acetate is a female hormone used for the research of endometriosis[1]. Norethindrone acetate-d8 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-150544S

N-Desmethyl Selegiline-d5 hydrochloride		Alkynes
N-Desmethyl Selegiline-dd₅ hydrochloride is the deuterium labeled N-Desmethyl Selegiline hydrochloride[1]. N-Desmethyl Selegiline-d5 hydrochloride is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-145472

Sphingosine (d18:1) alkyne

Alkynes

Sphingosine (d18:1) alkyne (compound 2b) is an alkyne-labeled Sphingosine (d18:1) that can be used in click chemistry reactions .


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MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
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Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

MCE Kits

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Hydroxychloroquine EP impurity D-d<sub>5</sub>

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

MCE Kits

Inhibitory Antibodies

NaturalProducts

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Natural
Products